The Effects of Exposure to 900 MHz Radiofrequency Radiation and Nicotine on Apoptotic Ratio of Human Fetal Cells

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Mustafa Emre
Ayper Boga
Salih Cetiner
Erdal Tunc
Osman Demirhan

Abstract

AIM: The present study purposes to examine the effects of radiofrequency electromagnetic radiation (RF-EMR) and nicotine exposures on apoptosis and necrosis ratio of cultured amniocytes.


METHODS: Amniotic fluid samples were gained from 48 pregnant women and, after culturing procedure, samples were analyzed by flow cytometry.


RESULTS: Significant increases were observed in ratios of necrotic (UL), early (LR), and late apoptotic cells (UR) in the exposure groups of RF-EMR, nicotine, and RF-EMR + nicotine groups (p < 0.01 and p < 0.001), along with significant changes in ratios of viable (LL) cells (p < 0.001).


CONCLUSION: Our results showed that nicotine exposure, alone or in combination with 900 MHz RF-EMR, led to increased apoptotic cell ratios. Amniocytes were even more severely affected by nicotine, when nicotine was administered in combination with 900 MHz RF-EMR, due to created synergistic effect. More studies with different settings, exposure times, frequencies, and doses are needed to clarify net effects of exposures to nicotine and RF-EMR radiation, alone or in combination.

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How to Cite
1.
Emre M, Boga A, Cetiner S, Tunc E, Demirhan O. The Effects of Exposure to 900 MHz Radiofrequency Radiation and Nicotine on Apoptotic Ratio of Human Fetal Cells. SEE J Immunol [Internet]. 2021 Nov. 26 [cited 2024 Mar. 19];4(1):1-7. Available from: https://seejim.eu/index.php/seejim/article/view/3249
Section
Basic Immunology