Advanced Platelet-rich Fibrin versus Sticky Bone in Socket Preservation - Clinical and X-ray Assessment: Case Report

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Stavre Trajculeski
Daniela Veleska-Stevkovska
Marija Trajculeski


BACKGROUND: The preservation of post-extraction alveola, as part of guided bone regeneration, is recommended for the creation of a biological foundation for future implant-prosthetic or prosthetic production. Several graft materials are used, either independently or in a combination of each other. Advanced platelet-rich fibrin (A-PRF) as an autologous blood derivate in the recent years has been increasingly used because of its properties in angiogenesis, epithelialization, and hemostasis. Simple production, low cost, and non-use of anticoagulants are advantages for more mass use of it.

CASE PRESENTATION: Two clinical cases are described, one is using a combination of A-PRF with xenograft, and the second clinical case is using a solo A-PRF, for socket preservation.

CONCLUSION: The properties of A-PRF for preserving both bone volume and quality have been confirmed, highlighting its potential as a valuable therapeutic tool. Furthermore, the post-operative period following A-PRF treatment has been found to be free of significant discomfort and morbidity for patients, suggesting that this approach may represent a safe and effective means of promoting optimal clinical outcomes.


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Trajculeski S, Veleska-Stevkovska D, Trajculeski M. Advanced Platelet-rich Fibrin versus Sticky Bone in Socket Preservation - Clinical and X-ray Assessment: Case Report. SEE J Immunol [Internet]. 2023 Jun. 6 [cited 2024 Apr. 16];6(1):12-7. Available from:
Basic Immunology


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