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Takayasu arteritis (TA) is an idiopathic chronic granulomatous vasculitis that affects aorta, its main branches and occasionally pulmonary arteries. It is more common in Asian persons, affecting predominantly young women. Clinical presentation is nonspecific at the beginning of the disease, while in the ischemic disease's stage it depends on the territories affected. We present the case of a 26-year-old woman who was diagnosed as having TA. Multiple vascular abnormalities of aorta and its branches and severely reduced left ventricular function were present at the time of diagnosis. Immunosuppressive treatment consisting of prednisone and azathyoprine along with conventional heart failure therapy significantly improved her cardiac function.
Johnston SL, Lock RJ, Gompels MM. Takayasu arteritis: a review. J Clin Pathol. 2002;55:481-6.
Richards BL, March L, Gabriel SE. Epidemiology of large-vessel vasculitides. Best Pract Res Clin Rheumatol. 2010;24:871-3.
Maffei S, Di Renzo M, Bova G, Auteri A, Pasqui AL. Takayasu's arteritis: a review of the literature. Intern Emerg Med. 2006; 1:105-12.
Nazareth R, Mason JC. Takayasu arteritis: severe concequences of delayed diagnosis. QJM. 2011;104:797-800.
Mason JC. Takayasu arteritis-advances in diagnosis and management. Nat Rev Rheumatol. 2010;6:406-15.
Kerr GS, Hallahan CW, Giordano J, Leavitt RY, Fauci AS, Rottem M, Hoffman GS. Takayasu arteritis. Ann Intern Med. 1994;120:919-29.
Johnston SL, Lock RJ, Gompels MM. Takayasu arteritis: a review. J Clin Pathol. 2002;55:481–6.
Park MC, Lee SW, Park YB, Chung NS, Lee SK. Clinical characteristics and outcomes of Takayasu's arteritis: Analysis of 108 patients using standardized criteria for diagnosis, activity assessment, and angiographic classification. Scand J Rheumatol. 2005;34:284-92.
Arend WP, Michel BA, Bloch DA, Hunder GG, Calabrese LH, Edworthy SM, Fauci AS, Leavitt RY, Lie JT, Lightfoot RW Jr, et al. The American College of Rheumatology 1990 criteria for the classification of Takayasu arteritis. Arthritis Rheum. 1990;33:1129-34.
Lambert M, Hatron PY, Hachulla E, Warembourg H, Devulder B. Takayasu's arteritis diagnosed at the early systemic phase: diagnosis with noninvasive investigation despite normal findings on angiography. J Rheumatol. 1998;25:376–7.
Tann OR, Tulloh RM, Hamilton MC: Takayasu's disease: a review. Cardiol young 2008;18:250–9.
Hoffman GS, Ahmed AE. Surrogate markers of disease activity in patients with Takayasu arteritis. A preliminary report from The International Network for the Study of the Systemic Vasculitides (INSSYS). Int J Cardiol. 1998;66(Suppl. 1):S191–4.
Takeda N, Takahashi T, Seko Y, Maemura K, Nakasone H, Sakamoto K, Hirata Y, Nagai R. Takayasu myocarditis mediated by cytotoxic T lymphocytes. Intern Med. 2005;44:256-60.
Talwar KK, Chopra P, Narula J, Shrivastava S, Singh SK, Sharma S, Saxena A, Rajani M, Bhatia ML. Myocardial involvement and its response to immunosuppressive therapy in nonspecific aortoarteritis (Takayasu's disease) a study by endomyocardial biopsy. Int J Cardiol. 1988;21:323–334.
Yang L, Zhang H, Jiang X, Zou Y, Qin F, Song L, Guan T, Wu H, Xu L, Liu Y, Zhou X, Bian J, Hui R, Zheng D. Clinical manifestations and longterm outcome for patients with Takayasu arteritis in China. J Rhumatol. 2014;41:2439-2446.
Kasashima S, Zen Y, Kawashima A, Endo M, Matsumoto Y, Kasashima F, Ohtake H, Nakanuma YJ. A clinicopathologic study of immunoglobulin G4-related sclerosing disease of the thoracic aorta. Vasc Surg. 2010;52:1587-1595.
Maksimowicz-McKinnon K, Clark TM, Hoffman GS. Limitations of therapy and a guarded prognosis in an American cohort of Takayasu arteritis patients. Arthritis Rheum. 2007;56:1000–9.
Kotter I, Henes JC, Wagner AD, Loock J, Gross WL. Does glucocorticosteroid-resistant large-vessel vasculitis (giant cell arteritis and Takayasu arteritis) exist and how can remission be achieved? A critical review of the literature. Clin Exp Rheum. 2012;30:S114-129.
Clifford A, Hoffman GS. Resent advances in the medical management of Takayasu arteritis: un update on use biologic therapies. Curr Opin Rheumatol. 2014;26:7-15.
Isobe M. Takayasu arteritis revisited: current diagnosis and ttreatment. Int J Cardiol. 2013;168:3-10.
Giordano JM. Surgical treatment of Takayasu's Arteritis. Int J Cardiol. 2000;75:S123-28.
Dagna L, Salvo F, Tiraboschi M, Bozzolo EP, Franchini S, Doglioni C, et al. Pentraxin-3 as a marker of disease activity in Takayasu's arteritis. Ann Intern Med. 2011;155:425-433.
Yamashita H, Kubota K, Mimori A. Clinical value of whole-body PET/CT in patients with active rheumatic diseases. Arthritis Res Ther. 2014;16:423-35.
Santhosh S, Mittal BR, Gayana S, Bhattacharya A, Sharma A, Jain S. F-18FDG PET/CT in the evaluation of Takayasu arteritis: an experience from the topics. J Nucl Cardiol. 2014;21:993-1000.